HSA coated MnO nanoparticles with prominent MRI contrast for tumor imaging.

نویسندگان

  • Jing Huang
  • Jin Xie
  • Kai Chen
  • Lihong Bu
  • Seulki Lee
  • Zhen Cheng
  • Xingguo Li
  • Xiaoyuan Chen
چکیده

We report in this Communication a facile, two-step surface modification strategy to achieve manganese oxide nanoparticles with prominent MRI T1 contrast. In a U87MG glioblastoma xenograft model, we confirmed that the particles can accumulate efficiently in tumor area to induce effective T1 signal alteration.

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عنوان ژورنال:
  • Chemical communications

دوره 46 36  شماره 

صفحات  -

تاریخ انتشار 2010